09.10.2012, 17:49
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#552
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Was neues zum Thema Darmflora aus London....
...und diesmal mit einer eindeutigen Bezugnahme auf Paläolithische Ernährung und Paleo-Lifestyle:
Pharmacol Res. 2012 Sep 16. pii: S1043-6618(12)00166-1. doi: 10.1016/j.phrs.2012.09.002. [Epub ahead of print]
Gut microbiota, immune development and function.
Bengmark S.
Division of Surgery & Interventional Science, University College London
Zitat:
Abstract
The microbiota of Westerners is significantly reduced in comparison to rural individuals living a similar lifestyle to our Paleolithic forefathers but also to that of other free-living primates such as the chimpanzee.
The great majority of ingredients in the industrially produced foods consumed in the West are absorbed in the upper part of small intestine and thus of limited benifit to the microbiota. Lack of proper nutrition for microbiota is a major factor under-pinning dysfunctional microbiota, dysbiosis, chronically elevated inflammation, and the production and leakage of endotoxins through the various tissue barriers.
Furthermore, the over consumption of insulinogenic foods and proteotoxins, such as advanced glycation and lipoxidation molecules, gluten and zein, and a reduced intake of fruit and vegetables, are key factors behind the commonly observed elevated inflammation and the endemic of obesity and chronic diseases, factors which are also likely to be detrimental to microbiota.
As a consequence of this lifestyle and the associated eating habits, most barriers, including the gut, the airways, the skin, the oral cavity, the vagina, the placenta, the blood-brain barrier, etc., are increasingly permeable.
(...)
Dramatic alterations, in direction of a paleolithic-like lifestyle and food habits, seem to be the only alternatives with the potential to control the present escalating crisis. The present review focuses on human studies, especially those of clinical relevance.
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