Zitat:
Zitat von sebBo
|
Ich habe vor ein paar Jahren selbst an so eine Studie im Saarland teilgenommen. Meines bescheidenen wissens nach wurde dieses Enzym auch festgestellt, aber es wurde auch gezeigt, dass es eben den Herzmuskel nicht schädigt.
Ich wurde wohl nach dem MTB Marathon ins St. Wendel ausgewählt, weil meine Indikatoren besonders auf eine Schädigung hinwiesen. Bei einem 2. Test in Saarbrücken, unter anderem Ultraschalluntersuchungen am Herzen währen der Belastung (Puls >160) und auch ein neuartiges farbiges Ultraschall, ergaben aber keine Schädigung des Herzmuskels.
Ich suche mal die Studie heraus.
so gefunden :D Der letzte Absatz ist wohl entscheidend.
Independent elevations of N-terminal pro–brain natriuretic peptide and cardiac troponins in endurance athletes after prolonged strenuous exercise
Jürgen Scharhag, MDaCorresponding Author Informationemail address, Markus Herrmann, MDab, Axel Urhausen, MD, PhD, FACSMc, Michaela Haschkea, Wolfgang Herrmann, MD, PhDb, Wilfried Kindermann, MD, PhDa
Received 2 November 2004; accepted 5 January 2005
Background
Although elevated resting brain natriuretic peptide (BNP) concentrations reflect heart disease, the meaning of exercise-induced increases is poorly understood and has been examined in small groups only. Therefore, the present study aimed to examine the increase in N-terminal pro–brain natriuretic peptide (NT-proBNP) and relations to cardiac troponin I and T (cTnI, cTnT) elevations after prolonged strenuous exercise in a large cohort of athletes.
Methods
We examined exercise-induced changes in NT-proBNP, cTnI, and cTnT in 105 obviously healthy endurance athletes (40 ± 8 years) before and after prolonged strenuous exercise. Blood samples were taken before, 15 minutes, and 3 hours after a marathon (n = 46), a 100-km run (n = 14), and a mountain bike marathon (n = 45).
Results
Eighty-one of 105 athletes exceeded the upper reference limit of NT-proBNP (males/females 88:153 ng/L) after exercise. NT-proBNP increased in all 3 events (P < .001) with the highest increase in the 100-km runners (median increase 200 ng/L; 25th/75th percentile 115/770 ng/L), which differed from the increase in the marathon (97 ng/L; 36/254 ng/L) or the mountain bike marathon (78 ng/L; 37/196 ng/L) (P < .01). Cardiac troponin I exceeded 0.04 μg/L in 74%; cTnT exceeded 0.01 μg/L in 47% of athletes after exercise. NT-proBNP was not related to exercise-induced increases in cTnI or cTnT, but correlated with exercise time (r = 0.55, P < .001).
Conclusions
Increases in NT-proBNP can be found in a major part of obviously healthy athletes after prolonged strenuous exercise. The release of BNP during and after exercise may not result from myocardial damage but may have cytoprotective and growth-regulating effects. The different nature of exercise-induced increases in BNP and cardiac troponins has to be elucidated in the future.e
gemeinsam zwiften |
youtube |
forum heute
Rechner
